Why should you choose the Qualified® prenatal test
- The Qualified Prenatal Test can be performed as early as the 9th week of pregnancy
- Qualified Test results are available within 2–3 business days from the date the sample is received by the laboratory
Options of Qualified® prenatal test
Qualified® 90°
Trisomies 21, 18, 13
Sexual aneuploidies
Qualified® 120°
Trisomies 21, 18, 13
Sexual aneuploidies
DiGeorge syndrome
Qualified® 180°
Trisomies 21, 18, 13
Sexual aneuploidies
All deletions and duplications (CNVs) ≥ 7Mb
Qualified® 360°
Aneuploidies (trisomies and monosomies) of all chromosomes (1-22)
Sexual aneuploidies*
All deletions and duplications (CNVs) ≥ 7mb**
Qualified® 6m
Trisomies 21, 18, 13
Sexual aneuploidies
All deletions and duplications (CNVs) ≥ 7Mb
Microdeletions <7mb (6 basic)***
Qualified® 9m
Aneuploidies (trisomies and monosomies) of all chromosores (1-22)
Sexual aneuploidies*
All deletions and duplications (CNVs] ≥ 7mb**
Microdeletions <7mb (9 most common)***
Qualified® 23m
Aneunloidies [trisomies and monosomies] of all chromosomes (1-22)
Sexual aneuploidies*
All deletions and duplications (CNVs) ≥ 7mb**
Microdeletions <7mb (all 23)***
Initiative test (SMA & CF)
Qualified® One
Aneuploidies (trisomies and monosornies) of all chromosomes (1-22)
Sexual aneuploidies*
All deletions and duplications (CNVs) ≥ 7mb**
Microdeletions < 7mb (al 23)***
Initiative test (SMA & CF)
Monogenic diseases 100+**
Qualified® prenatal testing options for twin pregnancy
Qualified® Twin Basic
Trisomies 21, 18, 13
Presence of Y chromosome
Qualified® Twin 360°
Aneuploidies (trisomies and monosomies) of all chromosomes (1-22)
Presence of Y chromosome
All deletions and duplications (CNVs) > 7mb**
Qualified® Vanishing Twin
Trisomies 21, 18, 13
Presence of Y chromosome
Qualified® Signature
The Qualified® SignatureTM option consists of analyzes according to the wishes of pregnant women or the gynecologist's advice, with the assignment of a personal Qualified® SignatureTM advisor who will guide you at every step of the process.
WHY THE QUALIFIED® PRENATAL TEST?
- More detailed analysis (10-12 million readings per sample)
- SeQuel™ NIPT Solution is the most advanced 5D platform based on NGS technology
- The Qualified® prenatal test specificity is 99.9%
- The Qualified® is the only prenatal test that analyzes all 23 microdeletions 1-7Mb***
The most common sex chromosome aneuploidies are as follows:
- Turner syndrome (X0)
- Triple X (XXX)
- Klinefelter syndrome (XXY)
- Jacobsen syndrome (XYY)
Some options of Qualified® prenatal test analyze 512 genomic regions of interest, identifying anomalies that, as per current databases, could involve CNVs (Copy Number Variations)
Qualified® One additionally examines 100+ monogenic diseases which are caused by a mutation or change in only one gene. These changes can be inherited from parents or they can happen spontaneously (de novo). These diseases can be inherited in different ways, including autosomal dominant, autosomal recessive and X-linked inheritance, and some examples are cystic fibrosis, tuberous sclerosis, congenital deafness. This type of genetic testing helps in early mutation detection and risk assessment for future offspring in general, not only in the current pregnancy, which is important for planning families and timely medical intervention.
All 23 microdeletions ≤ 7mb:
- DiGeorge syndrome (22q11.2)
- 1p36 deletion syndrome
- Angelman syndrome (15q11.2)
- Prader-Willi syndrome
- Cri du Chat (5p-syndrome)
- Wolf-Hirschhorn syndrome (4p16.3)
- Jacobsen syndrome (11q23-q24.3)
- Langer-Giedion syndrome (8q24.11-q24.13)
- Smith-Magenis syndrome (17p11.2)
- 2q31.2 deletion syndrome
- 3q29 deletion syndrome
- Potocki-Lupski syndrome
- Alagille syndrome 1
- 7q11.23 syndrome
- Miller-Dieker syndrome (17p13.3)
- Pallister-Killian syndrome
- 15q11-q13 syndrome
- 15q14 deletion syndrome
- Xp21.1-21.2 deletion syndrome
- 17q11.2 deletion syndrome
- 17q12 deletion syndrome
- Koolen-De Vries syndrome
- Phelan-McDermin syndrome
THE INITIATIVE® IS A PREVENTATIVE SCREENING TEST ON SMA (SPINAL MUSCULAR ATROPHY) TYPES 1, 2, 3 AND 4 AS WELL AS FOR CF (CYSTIC FIBROSIS) INTENDED FOR PREGNANT WOMAN
THE INITIATIVE® TEST CAN BE DONE TOGETHER WITH ANY OPTION OF QUALIFIED® PRENATAL TEST
THE INITIATIVE® TEST IS INCLUDED IN THE PRICE OF THE QUALIFIED® 23m AND QUALIFIED® One OPTIONS
